The Markus Covert group’s Cell paper from last week represents a tremendous achievement toward a more systematic understanding of how biological cells work. For decades much of molecular and cellular biology has focused on single genes and single pathways. This was partly out of necessity given the cell’s astronomical complexity. And it was also due to evolutionary dogma which viewed the biological world as so many organic contraptions strapped together one way or another. The result was a rather limited perspective of cellular biology. As Bruce Alberts explained in 1998: Read more