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	<title>Comments on: The Schlafly-Lenski Briefwechsel</title>
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		<title>By: allanius</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-2/#comment-291504</link>
		<dc:creator>allanius</dc:creator>
		<pubDate>Thu, 26 Jun 2008 20:26:17 +0000</pubDate>
		<guid isPermaLink="false">http://www.uncommondescent.com/?p=3428#comment-291504</guid>
		<description>Lenski’s overreaction is worse than Schlafly’s overreaction; granted. But this is about strategy. 

Schlafly chose to badger Lenski about his results, presumably because he felt a need to respond to the Coynes of the world and outrageous claims that are being made based on the paper. Unfortunately this can come across as simple bad manners. Schlafly appears to be insinuating that Lenski is dishonest and bullying him with threats of legal action.

We don’t know if the results Lenski reported are accurate—and we’ll never know. It will never be possible to prove that no evolution occurred, even if the same study is repeated with negative results. The best Schlafly can hope for is a Pyrrhic victory.

We do know, however, that Lenski’s own conclusions are quite modest: “We demonstrated that the evolution of this new function was contingent on the history of the population in which it arose.” No attempt is made to use the results to support the theory of evolution per se. And except for a little self-indulgence at the end, the paper is restrained and free from tendentious polemic.

So is it better, from a strategic point of view, to attempt to score points against Lenski through confrontation, knowing in advance that no conclusive result is possible, or can more good perhaps be done by taking up pure, sweet reason and explaining why his results can be interpreted to support ID and undermine Darwin’s narrative of effortless progression?</description>
		<content:encoded><![CDATA[<p>Lenski’s overreaction is worse than Schlafly’s overreaction; granted. But this is about strategy. </p>
<p>Schlafly chose to badger Lenski about his results, presumably because he felt a need to respond to the Coynes of the world and outrageous claims that are being made based on the paper. Unfortunately this can come across as simple bad manners. Schlafly appears to be insinuating that Lenski is dishonest and bullying him with threats of legal action.</p>
<p>We don’t know if the results Lenski reported are accurate—and we’ll never know. It will never be possible to prove that no evolution occurred, even if the same study is repeated with negative results. The best Schlafly can hope for is a Pyrrhic victory.</p>
<p>We do know, however, that Lenski’s own conclusions are quite modest: “We demonstrated that the evolution of this new function was contingent on the history of the population in which it arose.” No attempt is made to use the results to support the theory of evolution per se. And except for a little self-indulgence at the end, the paper is restrained and free from tendentious polemic.</p>
<p>So is it better, from a strategic point of view, to attempt to score points against Lenski through confrontation, knowing in advance that no conclusive result is possible, or can more good perhaps be done by taking up pure, sweet reason and explaining why his results can be interpreted to support ID and undermine Darwin’s narrative of effortless progression?</p>
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		<title>By: Larry Fafarman</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-1/#comment-291485</link>
		<dc:creator>Larry Fafarman</dc:creator>
		<pubDate>Thu, 26 Jun 2008 17:21:50 +0000</pubDate>
		<guid isPermaLink="false">http://www.uncommondescent.com/?p=3428#comment-291485</guid>
		<description>Patrick said (#29) --

&lt;blockquote&gt;My first opinion of Schlafly’s behavior (and this was before Dave created this post) was that he was overreacting to Lenski’s work and making a fool of himself in the process. &lt;/blockquote&gt;

Schlafly overreacted because the Darwinists overreacted.

&lt;blockquote&gt;Lenski is not directly responsible for the way his work is being trumpeted as the salvation of Darwinism. Which I think is hilarious, considering it appears to be a confirmation of Behe’s main thesis if anything else. &lt;/blockquote&gt;

So far as I can see,   Lenski and his colleagues have not repudiated any of the overenthusiastic responses to the study.</description>
		<content:encoded><![CDATA[<p>Patrick said (#29) &#8211;</p>
<blockquote><p>My first opinion of Schlafly’s behavior (and this was before Dave created this post) was that he was overreacting to Lenski’s work and making a fool of himself in the process. </p></blockquote>
<p>Schlafly overreacted because the Darwinists overreacted.</p>
<blockquote><p>Lenski is not directly responsible for the way his work is being trumpeted as the salvation of Darwinism. Which I think is hilarious, considering it appears to be a confirmation of Behe’s main thesis if anything else. </p></blockquote>
<p>So far as I can see,   Lenski and his colleagues have not repudiated any of the overenthusiastic responses to the study.</p>
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		<title>By: Patrick</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-1/#comment-291482</link>
		<dc:creator>Patrick</dc:creator>
		<pubDate>Thu, 26 Jun 2008 15:08:29 +0000</pubDate>
		<guid isPermaLink="false">http://www.uncommondescent.com/?p=3428#comment-291482</guid>
		<description>gpuccio:

Agreed. My first opinion of Schlafly’s  behavior (and this was before Dave created this post) was that he was overreacting to Lenski&#039;s work and making a fool of himself in the process. And Lenski is not directly responsible for the way his work is being trumpeted as the salvation of Darwinism. Which I think is hilarious, considering it appears to be a confirmation of Behe&#039;s main thesis if anything else.</description>
		<content:encoded><![CDATA[<p>gpuccio:</p>
<p>Agreed. My first opinion of Schlafly’s  behavior (and this was before Dave created this post) was that he was overreacting to Lenski&#8217;s work and making a fool of himself in the process. And Lenski is not directly responsible for the way his work is being trumpeted as the salvation of Darwinism. Which I think is hilarious, considering it appears to be a confirmation of Behe&#8217;s main thesis if anything else.</p>
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		<title>By: gpuccio</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-1/#comment-291478</link>
		<dc:creator>gpuccio</dc:creator>
		<pubDate>Thu, 26 Jun 2008 13:34:03 +0000</pubDate>
		<guid isPermaLink="false">http://www.uncommondescent.com/?p=3428#comment-291478</guid>
		<description>My point of view:

Lenski has probably lost his temper a little bit, but Schlafly&#039;s attitude was totally unreasonable, so maybe Lenski is partially justified.

We have to distinguish bewteen what Lenski says in his paper and what others(either darwinists or IDists)have said, both in the news and on the blogs, and of which Lenski is not responsible. A lot of things have been said about that paper which are simply wrong, and do not bear any connection to what is written in the paper.

Lenski&#039;s paper, IMO, remains interesting, but is absolutely incomplete. Lenski should try to identify the mutation or mutations which characterize the Cit+ strain. Only then we can start reasoning about mechaninsms, evolutionary meanings, and so on. The main flaw in Lenski&#039;s paper is probably to try to jump to conslusions too early, and without having the necessary information.

So, I think we should all wait that the mutation is identified. Most of the false beliefs of darwinian evolution are based on generic reasoning, and fail to survive as soon as one goes into details. We should not make that error again. We need details, molecular details. Only then discussions about mechanisms become clear and strict.</description>
		<content:encoded><![CDATA[<p>My point of view:</p>
<p>Lenski has probably lost his temper a little bit, but Schlafly&#8217;s attitude was totally unreasonable, so maybe Lenski is partially justified.</p>
<p>We have to distinguish bewteen what Lenski says in his paper and what others(either darwinists or IDists)have said, both in the news and on the blogs, and of which Lenski is not responsible. A lot of things have been said about that paper which are simply wrong, and do not bear any connection to what is written in the paper.</p>
<p>Lenski&#8217;s paper, IMO, remains interesting, but is absolutely incomplete. Lenski should try to identify the mutation or mutations which characterize the Cit+ strain. Only then we can start reasoning about mechaninsms, evolutionary meanings, and so on. The main flaw in Lenski&#8217;s paper is probably to try to jump to conslusions too early, and without having the necessary information.</p>
<p>So, I think we should all wait that the mutation is identified. Most of the false beliefs of darwinian evolution are based on generic reasoning, and fail to survive as soon as one goes into details. We should not make that error again. We need details, molecular details. Only then discussions about mechanisms become clear and strict.</p>
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		<title>By: William Wallace</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-1/#comment-291455</link>
		<dc:creator>William Wallace</dc:creator>
		<pubDate>Thu, 26 Jun 2008 05:39:47 +0000</pubDate>
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		<description>Oops, sorry, you have seen it!

I do wonder what set off Lenski...the guy went postal.

That PZ &quot;brass knuckles&quot; Myers thinks Lenski is so great is not surprising, considering PZ&#039;s instability.</description>
		<content:encoded><![CDATA[<p>Oops, sorry, you have seen it!</p>
<p>I do wonder what set off Lenski&#8230;the guy went postal.</p>
<p>That PZ &#8220;brass knuckles&#8221; Myers thinks Lenski is so great is not surprising, considering PZ&#8217;s instability.</p>
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		<title>By: allanius</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-1/#comment-291438</link>
		<dc:creator>allanius</dc:creator>
		<pubDate>Thu, 26 Jun 2008 00:27:29 +0000</pubDate>
		<guid isPermaLink="false">http://www.uncommondescent.com/?p=3428#comment-291438</guid>
		<description>From the paper: 

“It is clearly very difficult for E. coli to evolve this function. In fact, the mutation rate of the ancestral strain from Cit- to Cit+ is immeasurably low; even the upper bound is 3.6 _ 10_13 per cell generation, which is three orders of magnitude below the typical base pair mutation rate. Nevertheless, one population eventually evolved the Cit+ function, whereas all of the others remain Cit- after more than 40,000 generations.”

Excuse the ignorance of a non-scientist, but doesn’t this show that micro-evolution is highly unlikely, even in a highly controlled environment favoring development of Cit+ E. Coli? In fact isn’t that what Lenski actually says? And isn’t there a distinct difference between Lenski’s rhetoric and what was seen in the New Scientist?</description>
		<content:encoded><![CDATA[<p>From the paper: </p>
<p>“It is clearly very difficult for E. coli to evolve this function. In fact, the mutation rate of the ancestral strain from Cit- to Cit+ is immeasurably low; even the upper bound is 3.6 _ 10_13 per cell generation, which is three orders of magnitude below the typical base pair mutation rate. Nevertheless, one population eventually evolved the Cit+ function, whereas all of the others remain Cit- after more than 40,000 generations.”</p>
<p>Excuse the ignorance of a non-scientist, but doesn’t this show that micro-evolution is highly unlikely, even in a highly controlled environment favoring development of Cit+ E. Coli? In fact isn’t that what Lenski actually says? And isn’t there a distinct difference between Lenski’s rhetoric and what was seen in the New Scientist?</p>
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		<title>By: Charlie</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-1/#comment-291434</link>
		<dc:creator>Charlie</dc:creator>
		<pubDate>Wed, 25 Jun 2008 22:56:15 +0000</pubDate>
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		<description>Not that we&#039;re voting, but I agree with tribune, DaveScot and Kike Behe on the significance of this work.

But, and as being very pro-ID this pains me to say, I understand Lenski&#039;s responses and find them more than justifiable.</description>
		<content:encoded><![CDATA[<p>Not that we&#8217;re voting, but I agree with tribune, DaveScot and Kike Behe on the significance of this work.</p>
<p>But, and as being very pro-ID this pains me to say, I understand Lenski&#8217;s responses and find them more than justifiable.</p>
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		<title>By: Larry Fafarman</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-1/#comment-291417</link>
		<dc:creator>Larry Fafarman</dc:creator>
		<pubDate>Wed, 25 Jun 2008 19:00:35 +0000</pubDate>
		<guid isPermaLink="false">http://www.uncommondescent.com/?p=3428#comment-291417</guid>
		<description>In comment #10,   I said,
&lt;blockquote&gt;At the end of each 24-hour period, only one percent of the old populations were transferred to start the next populations, and if only one, two, or just a few of the bacteria in an old population possessed a particular mutation, then it was likely that the mutation would not be transferred to the next population. I am wondering why only one percent of each population was transferred. &lt;/blockquote&gt;
 
I just want to add a few more thoughts.
 
Because there are few generations per daily population (44,000 generations in 20 years works out to an average of only 6 generations per day),   mutations in a population get little chance to propagate and hence it is especially likely that only one or just a few bacteria in a population will possess a particular mutation.   Thus,  there is a good chance that a mutation will be discarded because only one percent of an old population is used to start the next day&#039;s population.    It is not possible to save the whole population (otherwise the experiment would quickly run out of room) but IMO a more reasonable portion -- maybe half -- of the populations should be saved in order to minimize the risk of throwing out mutations.
 
I suspect that the second,  expressed mutation was fairly common because it was often repeated in populations descended from a frozen population of 20,000 generations or later,  and I suspect that the reason why it took so long for this mutation to be expressed the first time -- about 5 years (20,000th to 31,500th generations) -- was that a lot of mutations were discarded when the next day&#039;s population was started.</description>
		<content:encoded><![CDATA[<p>In comment #10,   I said,</p>
<blockquote><p>At the end of each 24-hour period, only one percent of the old populations were transferred to start the next populations, and if only one, two, or just a few of the bacteria in an old population possessed a particular mutation, then it was likely that the mutation would not be transferred to the next population. I am wondering why only one percent of each population was transferred. </p></blockquote>
<p>I just want to add a few more thoughts.</p>
<p>Because there are few generations per daily population (44,000 generations in 20 years works out to an average of only 6 generations per day),   mutations in a population get little chance to propagate and hence it is especially likely that only one or just a few bacteria in a population will possess a particular mutation.   Thus,  there is a good chance that a mutation will be discarded because only one percent of an old population is used to start the next day&#8217;s population.    It is not possible to save the whole population (otherwise the experiment would quickly run out of room) but IMO a more reasonable portion &#8212; maybe half &#8212; of the populations should be saved in order to minimize the risk of throwing out mutations.</p>
<p>I suspect that the second,  expressed mutation was fairly common because it was often repeated in populations descended from a frozen population of 20,000 generations or later,  and I suspect that the reason why it took so long for this mutation to be expressed the first time &#8212; about 5 years (20,000th to 31,500th generations) &#8212; was that a lot of mutations were discarded when the next day&#8217;s population was started.</p>
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		<title>By: bevets</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-1/#comment-291403</link>
		<dc:creator>bevets</dc:creator>
		<pubDate>Wed, 25 Jun 2008 16:39:29 +0000</pubDate>
		<guid isPermaLink="false">http://www.uncommondescent.com/?p=3428#comment-291403</guid>
		<description>But how are we to know if these traits weren&#039;t &#039;potentiated&#039; by the Creator when He designed the bacteria thousands of years ago, such that they would eventually reveal themselves when the time was right? ~ Dr. Paley

So, will we share the bacteria? Of course we will, with competent scientists. ~ Richard Lenski

Paging &lt;a href=&quot;http://www.museumofhoaxes.com/hoax/forum/forum_comments/1720/&quot; rel=&quot;nofollow&quot;&gt;&#039;Dr. Paley&#039;&lt;/a&gt;</description>
		<content:encoded><![CDATA[<p>But how are we to know if these traits weren&#8217;t &#8216;potentiated&#8217; by the Creator when He designed the bacteria thousands of years ago, such that they would eventually reveal themselves when the time was right? ~ Dr. Paley</p>
<p>So, will we share the bacteria? Of course we will, with competent scientists. ~ Richard Lenski</p>
<p>Paging <a href="http://www.museumofhoaxes.com/hoax/forum/forum_comments/1720/" rel="nofollow">&#8216;Dr. Paley&#8217;</a></p>
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		<title>By: bornagain77</title>
		<link>http://www.uncommondescent.com/intelligent-design/the-schlafly-lenski-briefwechsel/comment-page-1/#comment-291398</link>
		<dc:creator>bornagain77</dc:creator>
		<pubDate>Wed, 25 Jun 2008 15:21:28 +0000</pubDate>
		<guid isPermaLink="false">http://www.uncommondescent.com/?p=3428#comment-291398</guid>
		<description>Patrick,
 By whatever convoluted pathway that the e-coli utilized its preexisting citrate utilizing ability, My bottom dollar is on the fact that the citrate will be less fit in the original parent species environment when compared to parent species in that environment. I see nothing in all of Behe&#039;s work in Edge Of Evolution to make me think that complexity will ever be gained above parent species in its native environment. Evolution, must of necessity, demonstrate, at the very least, this minimal amount of complexity generation above the parent species in its native environment to be considered viable with its grand claims of generating all life in the first place. Though you bring up a viable point in that repair to a &quot;preexisting&quot; state of &quot;grand-parent&quot; strain, could produce a false positive for evolutionists, my first impression is that this repair to a preexistent grand-parent species state would require to many steps, and would border on, if not surpass, Behe&#039;s Edge. Genetic Entropy, by all rights, should be expected to hold in this case.</description>
		<content:encoded><![CDATA[<p>Patrick,<br />
 By whatever convoluted pathway that the e-coli utilized its preexisting citrate utilizing ability, My bottom dollar is on the fact that the citrate will be less fit in the original parent species environment when compared to parent species in that environment. I see nothing in all of Behe&#8217;s work in Edge Of Evolution to make me think that complexity will ever be gained above parent species in its native environment. Evolution, must of necessity, demonstrate, at the very least, this minimal amount of complexity generation above the parent species in its native environment to be considered viable with its grand claims of generating all life in the first place. Though you bring up a viable point in that repair to a &#8220;preexisting&#8221; state of &#8220;grand-parent&#8221; strain, could produce a false positive for evolutionists, my first impression is that this repair to a preexistent grand-parent species state would require to many steps, and would border on, if not surpass, Behe&#8217;s Edge. Genetic Entropy, by all rights, should be expected to hold in this case.</p>
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