Home » Intelligent Design » Solexa: A development which may lead to measuring claims of ID proponents

Solexa: A development which may lead to measuring claims of ID proponents

Some of the claims by ID proponents have not been adequately explored because of the cost issues involved in doing large-scale whole-genome sequencing of numerous individuals. Not even Warren Buffet has the trillions of dollars needed to accomplish such a massive amount of gene sequencing. At least not today, but maybe in the future!

The human genome project took 3 billion dollars and 13 years to complete. By comparison, Solexa might be able to do a comparable job for a few thousand dollars per person (ideally even less) and in a much shorter time frame. (See the UD sidebar on Solexa Genomics.) Solexa might be viewed as an unwitting research partner of the ID movement.

The fine work of two important ID proponents, Cornell geneticist John Sanford and independent researcher Walter ReMine, might finally get slam dunk empirical confirmation if Solexa succeeds in its grand quest. For example, a fundamental consequence of Sanford’s Genetic Entropy thesis is that there will be an unabated rise in Single Nucleotide Polymorphisms (SNPs) per generation per individual. If confirmed, this data will be more nails in Darwin’s coffin, and then Darwin Day might have to be renamed Darwin Bashing Day (or something else, how about Abe Lincoln Day?).

Solexa, Inc. is developing and commercializing the Solexa Genome Analysis System, which is being used to perform a range of analyses including whole genome resequencing, gene expression analysis and small RNA analysis. Solexa expects its first-generation instrument, the 1G Genome Analyzer, to generate over a billion bases of DNA sequence per run and to enable human genome resequencing below $100,000 per sample, making it the first platform to reach this important milestone. Solexa’s longer-term goal is to reduce the cost of human re-sequencing to a few thousand dollars for use in a wide range of applications from basic research through clinical diagnostics. For further information, please visit www.solexa.com.

Update: I should add, Solexa’s technology is poised to provide data which will overturn the prevailing ideas about molecular clocks (See: Molecular Clocks: Michael Denton continues to be vindicated). I will elaborate in the comment section if anyone is interested. In brief, we do not have accurate measurements of molecular evolution to the degree needed to overturn certain hypotheses. The increased accuracy provided by Solexa technology could permanently shatter the prevailing molecular clock hypothesis and vindicate various claims of ID proponents.

Update: Solexa’s technology will also aid in the ID quest of steganography in biology. If the key to rapidly understanding the steganography in junkDNA is through comparative sequencing of various creatures, Solexa’s technology is a welcome friend. I would like to also acknowledge again the fine work of Dr. Pellionisz on JunkDNA. I expect he will be delighted by the work of Solexa. Here is the latest from Dr. Pellionisz comment 87430

  • Delicious
  • Facebook
  • Reddit
  • StumbleUpon
  • Twitter
  • RSS Feed

8 Responses to Solexa: A development which may lead to measuring claims of ID proponents

  1. I also am delighted to point out president John West of Solexa (not John West of Discovery Institute, CSC), is an engineer. The officers of Solexa specialize in Chemistry and Engineering.

    Mr. West holds BS and MS degrees in
    engineering from MIT and an MBA in Finance from the Wharton School at
    the University of Pennsylvania.

    This symbolizes the fact that evolutionary biology (with the exception of the very admirable field of operational population genetics and fine evolutioanry biologists like Richard Sternberg) is becoming scientifically irrelevant to the emerging high-tech biotech industry.

    Systems Biology (an ID-sympathetic engineering perspective) will be the dominant paradigm for describing biological systems. Evolutionary biology will find itself largely irrelevant to modern science and technology…..

    The perspective of engineering and information science will infuse the biological disciplines of the future. This Systems perspective gives design priority over natural selection in interpreting biological systems.

    Now that money is on the line, pragmatism will make irrelevant Darwinist ideology in the high-tech industry.

  2. Be careful, Sal. Evolutionary computing is a tool of the high-tech industry, so I can see this tool being used to justify the power of natural selection. The way to counter this move is to show that evolutionary computing is itself thoroughly teleological. This is an ongoing project of mine.

  3. Solexa’s technique may also lead to accurate calibration of REAL molecular clocks versus the fake molecular clocks mentioned here: Molecular Clocks: Michael Denton continues to be vindicated.

    Solexa’s science might put an end to much of the fake molecular clock ideas when their technology paves the way for calibrating the REAL clocks in REAL life. Thousands of peer reviewed papers, possibly entire departments of evolutionary biology will be up-ended in the face of empirical data which Solexa’s technology might finally make accessible.

  4. Be careful, Sal. Evolutionary computing is a tool of the high-tech industry, so I can see this tool being used to justify the power of natural selection. The way to counter this move is to show that evolutionary computing is itself thoroughly teleological. This is an ongoing project of mine.

    Agreed. Many systems like VLSI circuit design are derived in part via evolutionary computing. Unfortunately, the word “evolution” has been too strongly associated with atelic processes, and this atelic view dominates much of evolutionary biology.

    It would be helpful if the word evolution were decoupled from its atelic associations.

  5. Many systems like VLSI circuit design are derived in part via evolutionary computing.

    Yeah. And before computers we did our VLSI designs by evolutionary mechanical penciling. Trial and error isn’t anything new. It’s so simple…

    http://youtube.com/watch?v=SMeeSIPncUQ

  6. […] Here I suggested in 2007, there will be almost unabated growth of mild, almost undetectable defects […]

  7. […] These considerations lead to scientifically testable predictions related to ENCODE, junk DNA and deeply conserved sequences. If the deeply conserved sequences are evolving in the present day according to neutral evolution, then how did they arise in the first place and remain conserved? It might be difficult to test this because of the expense, but what might we find when it is eventually done right. I’ve predicted rise in SNP’s in conserved regions since January 2007 here. […]

  8. […] predicted rise in Single Nucleotide Polymorphisms in conserved regions since January 2007 here. I discussed this idea with Dr. Sanford and Dr. Carter at ICC 2013, and they were enthusiastic […]

Leave a Reply