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Blind cave fish see the light

Two blind fish can make sighted offspring.

“The offspring of crossbred blind cave fish see like their surface-dwelling cousins.

The results in Current Biology 1, show that the two populations took different evolutionary paths to blindness.

“We’ve basically shown that these different populations have converged upon the same outward appearance independently, and that they use different genes to do it”, says Richard Borowsky of New York University.”

This is the type of thing that RM and NS can do. I would say that they lose different genes to become blind, not use different genes.

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35 Responses to Blind cave fish see the light

  1. Well, PaV – show us your evidence. And also how it would explain the data in the paper (e.g. how you get 12 estimated QTLs if the inheritance isn’t genetic, and also the pattern of complementation).

    Bob

  2. I would also want to see PaV’s evidnece relating to a mechanism whereby disuse of eyes is the trigger for eye-development repressing RNA to bee transmitted to its offspring.

  3. 34

    Mutations can break things easily; it’s much harder to make things. There are many possible ways a mutation could break eyesight (think of all the causes of human blindness for comparison). So ‘when you cross them, the genetic deficiencies in one lineage are compensated for by strengths in the other, and vice-versa.’

    The evos would be onto something if they could find a mutation that could generate sight de novo, instead of merely allowing already-existing sight information to be expressed.

    See CMI’s article Let the blind see … Breeding blind fish with blind fish restores sight.

  4. [...] bacteria evolve antibiotic resistance by junking intricate machinery, not by creating it. Cave fish lose their eyes. But we don’t need a theory for how intricate machinery gets wrecked. We need a theory [...]

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