Another accidental use for “junk DNA”

_{Denyse O'Leary

October 7, 2016

'Junk DNA', Intelligent Design, News}

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mouse embryo showing enhancer activity (blue stain) in heart/Berkeley Labs

Researchers have shown that when parts of a genome known as enhancers are missing, the heart works abnormally, a finding that bolsters the importance of DNA segments once considered “junk” because they do not code for specific proteins.

…

“The cardiac changes that we observed in knockout mice lacking these enhancers highlight the role of noncoding sequences in processes that are important in human disease,” said study co-senior author Axel Visel, senior staff scientist and one of three lead researchers at the Mammalian Functional Genomics Laboratory, part of Berkeley Lab’s Environmental Genomics and Systems Biology (EGSB) Division. “Identifying and interpreting sequence changes affecting noncoding sequences is increasingly a challenge in human genetics. The genome-wide catalog of heart enhancers provided through this study will facilitate the interpretation of human genetic data sets.” Paper. (public access) – Diane E. Dickel, et al., Genome-wide compendium and functional assessment of in vivo heart enhancers. Nature Communications, 2016; 7: 12923 DOI: 10.1038/NCOMMS12923 More.

See also: Formerly thought “junk DNA,” lncRNA guides development of heart muscle cells

and

The latest in functional junk DNA

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From: PhysOrg
Telomeres stay intact in most cancer cell types by means of a specialized enzyme called telomerase that adds the repetitive telomere DNA sequences to the ends of chromosomes. Cancer cells can also use a second method involving a DNA-repair-based mechanism, called alternative lengthening of telomeres, or ALT for short. In general, cancer cells take over either type of telomere maintenance machinery to become immortal. Overall, about fifteen percent of cancers (those of cartilage, bone, and brain, for example) use the ALT process for telomere lengthening and maintenance.
PaV_{October 19, 2016
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Ahmedkiaan @ 70: More rubbish from the atheist fool who continues to come back for more lessons. That's good, son. Keep coming back. Maybe you will learn something from one of the more compassionate members here. They have more patience with fools like you than I do.Truth Will Set You Free_{October 17, 2016
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AK: Either illuminate, or remain silent.PaV_{October 17, 2016
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If the vast medical knowledge on HIV is completely erroneous, not only is that an extremely important story for humankind, but it would also establish the lies and deceit of the scientific community, which would reinforce ID. In other words, if you are correct, you--and the world--have an enormous amount to gain by fully and comprehensively making the case, and you have a platform for it, right here, and you could make the case immediately, on the front page of this very website. By contrast, I have nothing to gain by explaining anything, so I won't. I hope to see a full, powerful case laid out against HIV science. It could be a very productive and informative thread!AhmedKiaan_{October 17, 2016
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PaV @ 68: Don't hold your breath waiting to be illuminated by that one. He is without understanding. Thinking themselves wise...Truth Will Set You Free_{October 17, 2016
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AK: I ask you to illuminate us; and your response is to ask me to illuminate you. Please, go first.PaV_{October 17, 2016
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You got me there, by golly. Checkmated me. Sure did!Truth Will Set You Free_{October 17, 2016
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TWSYF, I think its about time you started. Your condition may be treatable.Pindi_{October 16, 2016
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I don't take meds. Never have. Are you really concerned about my health...Swine?Truth Will Set You Free_{October 16, 2016
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TWSYF - have you perchance been skipping your meds? You sound like you are about to explode.Pindi_{October 16, 2016
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Ahmedkiaan @ 62: My God, man. Do us all a favor and die already. It doesn't really matter does it...if you die? Be gone and do the world a favor. It's all just a bunch of molecules changing places anyway. What does it matter?Truth Will Set You Free_{October 16, 2016
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In fact I will cease bothering you on this thread and eagerly await an upcoming post where you outline the situation as you see it, and the relevant issues and questions, described in your own terms so there is no confusion. I think it would be a potentially very fruitful thread.AhmedKiaan_{October 16, 2016
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PaV, if you have serious objections to the medical knowledge regarding HIV, AIDS, the evolution of the virus, etc. you should take the opportunity to write up a front-page post comprehensively explaining your view of the situation, asking what you think are the pertinent questions, and so forth. This is a big, big topic, and it deserves its own thread.AhmedKiaan_{October 16, 2016
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AK: I'm glad you're amazed. Now, what about responses? You're free to illuminate. I will admit that the example of tuberculosis is a bit exaggerated, but only to make the point of the very bizarre manner in which HIV/AIDS is handled. I don't think there's ever been anything before like what we see happening with HIV/AIDs.PaV_{October 15, 2016
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"Ahmed is relatively new to this forum and up to this point it has been abundantly clear that he struggles to understand the issues being discussed here, " To be fair, any educated person would struggle to understand what is going on here.AhmedKiaan_{October 15, 2016
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LOL. My national CAP microbio license expired over a decade ago. Your notions are ...amazing.AhmedKiaan_{October 15, 2016
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AK: Does it amaze you that someone distrust the "scientific consensus" on HIV? It amazes me that the questions Duesberg asked in 1987 have yet to be answered. BTW, what "disease" does HIV 'cause'? Rubella produces rubella, and mumps produces mumps, and polio causes polio. What does HIV cause? Well, any one of a list of 24 diseases. So, for example, if you die from tuberculosis and they test your blood and find HIV present (the antibodies at least), then that person didn't die of tuberculosis, but of AIDS. Who has ever heard of such a thing? Haven't you the courage to ask difficult questions? Are you like the U.S. media, compliant?PaV_{October 15, 2016
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AhmedKiaan: Holey moley
Ahmed is relatively new to this forum and up to this point it has been abundantly clear that he struggles to understand the issues being discussed here, but today he makes a point. Well done Ahmed! "Holey moley" indeed. Why is it "anti-science" to ask questions like:
... if HIV starts in Africa and spreads to America, surely there would ‘outbreaks’ along the way, right? Well, where are they?
Origenes_{October 15, 2016
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Holy moley.AhmedKiaan_{October 14, 2016
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As to "Using the methods of evolutionary biology . . . " this only means that they know the mutation rate of the virus and they compare sequences. Has HIV become a squid? No. It only changes here and there. That's not evolution. That's change.PaV_{October 14, 2016
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wd400: Help me to understand your logic here: You say: "The oldest HIV viruses are from the late 50s, and come from ppl that died of AIDS associated diseases." I asked you this: "But it didn’t become AIDS until it got to San Francisco in the 1980’s? " If you state (following your wikipedia search) that someone had AIDS in the late 50's, this doesn't help explain in the least why the outbreak didn't occur somewhere in Africa---say, some major city. Again, why did it have to wait for over 20 years and then show up in San Francisco? Can you answer this? IOW, if HIV starts in Africa and spreads to America, surely there would 'outbreaks' along the way, right? Well, where are they? Duesberg argues that HIV is a passenger virus and hurts no one, and that immune suppression comes from the use of poppers (amyl nitrate) and drug use. His theory has the advantage of explaining why we first see it in San Francisco and not halfway between Africa and the Bay Area. Please help me understand this better.PaV_{October 14, 2016
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If you got as far as reading the article you'd know there is no virus from the 20s. Using the methods of evolutionary biology, scientists have inferred that the virus jumped to humans around the turn of the 20th century, and the pandemic strain arose in the Belgian Congo around the 20s. The oldest HIV viruses are from the late 50s, and come from ppl that died of AIDS associated diseases. If you asking why colonial doctors in the Belgian Congo didn't find AIDS you have a little too learn about colonialism in Africa. I'm not going to engage you any further on this topic. The reality of HIV and AIDS is so readily available for anyone can Google that it's not worth wasting time on contrarianism.wd400_{October 14, 2016
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But they do. There's HIV virus from the 20's.
From the 1920s until 1960, the pandemic HIV strain – there were others that fizzled out – spread from Kinshasa, crossed borders to other nations, and ultimately landed on distant continents. It has infected nearly 75 million people worldwide to date.
But it didn't become AIDS until it got to San Francisco in the 1980's? Is that suppose to make any sense at all? Your answer please.PaV_{October 14, 2016
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The answer to your question on 43 is "they don't". Someone that just wanted to know the truth should have no trouble working that out...wd400_{October 14, 2016
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All I ask is for explanations that make sense, and that are backed up with evidence. Along these lines, why don't you answer my question?PaV_{October 14, 2016
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Well you went and answered anyway: crank magnetism in full effect.wd400_{October 14, 2016
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From The History of Rubella and Rubella Vaccination Leading to Elimination
Congenital rubella syndrome (CRS) was discovered in the 1940s, rubella virus was isolated in the early 1960s, and rubella vaccines became available by the end of the same decade. Systematic vaccination against rubella, usually in combination with measles, has eliminated both the congenital and acquired infection from some developed countries, most recently the United States, as is confirmed by the articles in this supplement.
HIV was "discovered" in the early 80's. Where's the vaccine? Did you know that the HIV 'virus' has not really present in humans? You have to use a specific process on cell cultures before you see any 'virus' at all. HIV testing 'tests' for the presence of 'antigens,' not isolation of the virus itself.PaV_{October 14, 2016
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wd400: Answer my question first (@43), and then I'll answer yours.PaV_{October 14, 2016
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wd400,, speaking of antiscience positions, and since you personally believe that you are much, much, smarter than anyone who dares doubt unguided evolution built all the different lifeforms on earth in all their unfathomable complexities, perhaps you would like to tell us exactly why, since it has no rigid demarcation criteria, Darwinism qualifies as a science, instead of as a pseudo-science, in the first place? I know you think it beneath yourself to even acknowledge my existence on these pages, but I would appreciate it if you would humble yourself to teach us 'IDiots' and at least lay out the precise case for why you personally think unguided evolution even qualifies as a science, instead of a pseudo-science, in the first place. And when and if you honestly engage this subject, I will then happily show you why it does not qualify as a rigid science but is in fact a pseudo-science. Moreover, I will show you exactly why it qualifies as the most antiscientific theory to ever be advanced in the history of modern science.bornagain77_{October 13, 2016
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Are you actually adding HIV-AIDS denialsm to your quiver of antiscience positions?wd400_{October 13, 2016
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