Linc RNA–once believed useless–plays a role in the genome
|January 23, 2014||Posted by PaV under 'Junk DNA', Evolution|
Here is a piece over at Phys.Org dealing with “long, intergenic non-coding” RNA.
“When we removed the specific lincRNA, we looked at the mouse brain and the progenitors were reduced. As a consequence probably, the population [of neurons] that sits on top of the cerebral cortex are reduced … It’s likely that in the future we’ll see a number of studies showing that other lincRNAs are involved in specific behaviors,” Arlotta said. “The brain likes this junk RNA.”
Rinn and his colleagues have generated 18 strains of mutant mice, removing from each a different piece of “junk” genome, or so-called long intergenic noncoding RNAs (lincRNAs). If the lincRNA truly had been “junk,” nothing should have happened.
What the researchers found was the opposite. Obvious defects were observed in seven of the 18 mutant strains. Three died shortly after birth, and there is reason to believe many others also are defective. The authors reported these and more findings in the new online journal eLife, initiated by the Howard Hughes Medical Institute, the Wellcome Trust, and the Max Planck Institute.
I would speculate that all this “junk-DNA” has a profound role in the embryonic development of the brain–here I mean not only the Linc-RNA, but also other types of ncRNA, and also “pseudogenes.” I suspect that the Linc-RNAs, because of their length, might have something to do with the overall length of neurons within the brain. Some clever experimentalist should follow this up.
Meanwhile, we’re seeing a complete repudiation of Darwinian/evolutionary(population genetics) expectations.
ID predicts something: it turns out to be right. Darwinists/geneticsits predict something: it turns out to be wrong.
So much for the scientific method.
However–drum roll, please….–
Another day; another bad day for Darwinism!!!