Category: Genomics

Geoff Barnard Delivers Unwelcome News For Darwinism

Dr Geoff Barnard summarizes the evidence for his claim that the biggest challenge to Darwinism is not the survival of the fittest but rather the maintenance of fertility. more

Interactome? Well, remember genome, proteome, old folks home …

Interactome? Well, remember genome, proteome, old folks home … Old folks home? (For not-quite-dead-enough yet ideas like Darwinism) more

Guy who DOESN’T support ID: Genomics has “overturned” Darwin’s iconic Tree of Life

Guy who DOESN’T support ID: Genomics has “overturned” Darwin’s iconic Tree of Life more

Are exosomes the new “junk DNA”?

In “Exosome Explosion” (The Scientist , July 1, 2011), Clotilde Théry tells us “These small membrane vesicles do much more than clean up a cell’s trash—they also carry signals to distant parts of the body, where they can impact multiple dimensions of cellular life”: Secreted vesicles known as exosomes were first discovered nearly 30 years… more

Popcorn: How much of the genome is transcribed?

All? Some? None? Clark et al., The Reality of Pervasive Transcription: Current estimates indicate that only about 1.2% of the mammalian genome codes for amino acids in proteins. However, mounting evidence over the past decade has suggested that the vast majority of the genome is transcribed, well beyond the boundaries of known genes, a phenomenon… more

Biophysics: Long DNA terminal repeats have wrapping function, researcher finds

In “Kinky genes: Biophysics of DNA affects how it works” (New Scientist, 08 July 2011), MacGregor Campbell reports DNA is typically a long double-helical strand that can expose its sequences of base pairs. These are translated by RNA and particles called ribosomes into proteins, which do the cell’s work. When not in use, DNA wraps… more

Most life forms show S pattern in chromosome lengths, guess which one doesn’t?

From “Chromosomes’ Big Picture: Similarities Found in Genomes Across Multiple Species; Platypus Still out of Place” (ScienceDaily, July 11, 2011), we learn: “Basically what this all means is that if the chromosome number of a species can be given, the relative sizes of all the chromosomes can instantly be known,” Yu said. “Also, if you… more

Redwood trees’ genes differ from top to bottom

From “Environs Prompt Advantageous Gene Mutations as Plants Grow; Changes Passed to Progeny” (ScienceDaily, July 5, 2011) we learn: If a person were to climb a towering redwood and take a sample from the top and a sample from the bottom of the tree, a comparison would show that the two DNA samples are different.Christopher… more

A statistical comparison of two human genomes

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In a previous post I provided a statistical test to compare chimpanzee and human genomes. As you can read there, the post generated a very interesting discussion among the readers, and it seemed to me that the general feeling at the end was that my statistical method for performing genome-wide comparisons might have some merit,… more

Genome duplication and the limits of evolution

“Genome Duplication Encourages Rapid Adaptation of Plants” (ScienceDaily, May 4, 2011) While nearly all animals have two sets of chromosomes — one set inherited from the maternal parent and the other inherited from the paternal parent — many plants are polyploids, meaning they have four or more chromosome sets. “Some botanists have wondered if polyploids… more

Coffee!! Intelligent design found in DNA of a bacterium!

Of course, it was put there by a Canadian poet. Recently we learned that “An original piece of “living poetry” has been created in a lab in Canada.” Christian Bok encoded some of his verse into a DNA strip and got it inserted into an E.coli bacterium: Dr Bok used cryptography to embed his poem… more

“Evolution,” we are told, “can cause a rapid reduction in genome size”

From the Max Planck Institute, we learn (April 21, 2011): Despite being closely related to the lyre-leaved rock cress, the thale cress has a considerably smaller genomeIt would appear reasonable to assume that two closely related plant species would have similar genetic blueprints. However, scientists from the Max Planck Institute for Developmental Biology in Tübingen,… more

Should we always say it twice?: Identical twins are not really identical

From “No Two of Us Are Alike — Even Identical Twins: Pinpointing Genetic Determinants of Schizophrenia”, (ScienceDaily, March 28, 2011) we learn Singh looked at about one million markers of identical twins (and their two parents) where only one twin had schizophrenia. “The most informative feature of schizophrenia is that it sometimes runs in the… more

Diversity driven by imprinting, not selfish gene?

In this article in The Scientist, “Imprinting Diversity”, Cristina Luiggi interviews Joachim Messing about ways in which genomic imprinting may be a strong driver of diversity: Sexual reproduction yields offspring with two copies of the same gene, one from each parent; but in an epigenetic phenomenon known as genomic imprinting, only one copy of certain… more

Genomics: Hox Paradox described

A friend put me onto a “neat” summation of the “Hox paradox” in Bioscience last year: “Taken together, these findings presented researchers with a paradox. On one hand, the basic machinery underlying early development, such as the Hox genes, is widely conserved among divergent phyla. But at the same time, these genes also underlie the… more

Coffee!!: Sound of bubble bursting – getting real about genomic medicine

From ScienceDaily (Feb. 18, 2011) this news, “Promise of Genomics Research Needs a Realistic View, Experts Urge” Unrealistic expectations about genomic medicine have created a “bubble” that needs deflating before it puts the field’s long term benefits at risk, four policy experts write in the current issue of the journal Science. Ten years after the… more

Remember when the genome map was supposed to prove we were just apes?

Or sea slugs? Like, humans had 100, 000 genes, which proved we were a big-brained ape, then 30, 000, a bit more than a worm. Oh but wait, the fern has 250,000 genes and someone who has never kept a fern can be confident that they’re mostly junk. Now, ten years on, here’s the kind… more

World-record genome

SCIENCE: “Now THAT’s a genome. A rare Japanese flower named Paris japonica sports an astonishing 149 billion base pairs, making it 50 times the size of a human genome—and the largest genome ever found. Until now, the biggest genome belonged to the marbled lungfish, whose 130 billion base pairs weighed in at an impressive 132.83… more

Sanford’s pro-ID thesis supported by PNAS paper, read it and weep, literally

Cornell Geneticist John Sanford argued that Darwinism is wrong because the rate of genetic deterioration is so high that natural selection could not arrest it. If natural selection cannot arrest genetic deterioration, how then could it be the mechanism for evolutionary improvement? Sanford predicted through his research that human genome is deteriorating. This was a… more

A simple statistical test for the alleged “99% genetic identity” between humans and chimps

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Typical figures published in the scientific literature for the percentage similarities between the genomes of human beings (Homo sapiens) and chimpanzees (Pan troglodytes) range from 95% to 99%. However, in press releases intended for popular consumption, evolutionary biologists frequently claim that human and chimpanzee genomes are 99% identical. Skeptics of neo-Darwinian evolution have repeatedly punctured… more

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